Special Interest Group Meeting

Coordination of fungal development and secondary metabolism by light

Gerhard Braus, Molekulare Mikrobiologie und Genetik, Georg-August-Universität Göttingen

The homothallic filamentous ascomycete A. nidulans is able to form fruitbodies (cleistothecia) either by mating of two strains or by selfing in the absence of a partner. The three-dimensional A. nidulans cleistothecium is the most complicated structure this fungus is able to form. Differentiation and secondary metabolism are correlated processes in fungi that respond to various parameters including light, nutrients, aeration or pheromones. Our work on the dynamics of the formation of the heterotrimeric velvet complex VelB/VeA/LaeA will be described. VeA bridges VelB to the nuclear master regulator of secondary metabolism LaeA.VelB is part of a second complex and LaeA plays a key role in the crosstalk between both complexes.

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